rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2009-2-13
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pubmed:abstractText |
Obesity is one of the risk factors for non-alcoholic fatty liver disease (NAFLD) and a common disease that comprises simple steatosis and non-alcoholic steatohepatitis (NASH), and can eventually lead to liver cirrhosis. Adiponectin is an adipocyte-derived protein that has anti-obesity, antidiabetic and anti-inflammatory properties, and is considered to possess a hepatoprotective function. Its role in the development and progression of NAFLD in morbidly obese patients is unknown. In this study, we examined the expression levels of adiponectin and its receptors in liver biopsies of morbidly obese patients and then determined whether there was an association with the disease severity.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Feb
|
pubmed:issn |
1440-1746
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pubmed:author |
|
pubmed:issnType |
Electronic
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
233-7
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pubmed:meshHeading |
pubmed-meshheading:18713296-Adiponectin,
pubmed-meshheading:18713296-Adult,
pubmed-meshheading:18713296-Biopsy, Needle,
pubmed-meshheading:18713296-Disease Progression,
pubmed-meshheading:18713296-Down-Regulation,
pubmed-meshheading:18713296-Fatty Liver,
pubmed-meshheading:18713296-Female,
pubmed-meshheading:18713296-Hepatitis,
pubmed-meshheading:18713296-Humans,
pubmed-meshheading:18713296-Immunohistochemistry,
pubmed-meshheading:18713296-Liver,
pubmed-meshheading:18713296-Liver Cirrhosis,
pubmed-meshheading:18713296-Male,
pubmed-meshheading:18713296-Middle Aged,
pubmed-meshheading:18713296-Obesity, Morbid,
pubmed-meshheading:18713296-Receptors, Adiponectin,
pubmed-meshheading:18713296-Retrospective Studies,
pubmed-meshheading:18713296-Severity of Illness Index
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pubmed:year |
2009
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pubmed:articleTitle |
Expression of adiponectin and its receptors in livers of morbidly obese patients with non-alcoholic fatty liver disease.
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pubmed:affiliation |
Department of Endocrinology, Zhongshan Hospital Xiamen University, Xiamen, Fujian, China. mah-169@163.com
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pubmed:publicationType |
Journal Article,
Comparative Study
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