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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
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|
pubmed:dateCreated |
2008-8-20
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|
pubmed:abstractText |
Molecular characteristics of testosterone binding globulin (TeBG) were investigated in microaliquots of human serum samples using 3H-5-alpha-dihydrotestosterone radioligand assays. Under experimental conditions used TeBG demonstrated high conformational plasticity and ability to adopt three conformational states (olygo-, di-, and monomer) with different functional activities. Using alipidspolyene complex from basidiomycete Laetiporus sulphureus we demonstrate a novel effective pharmacological correction of the TeBG characteristics.
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pubmed:language |
rus
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:author |
|
|
pubmed:volume |
54
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
349-60
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|
pubmed:meshHeading |
pubmed-meshheading:18712090-Adolescent,
pubmed-meshheading:18712090-Animals,
pubmed-meshheading:18712090-Child,
pubmed-meshheading:18712090-Chromatography, Gel,
pubmed-meshheading:18712090-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:18712090-Female,
pubmed-meshheading:18712090-Humans,
pubmed-meshheading:18712090-Lipids,
pubmed-meshheading:18712090-Male,
pubmed-meshheading:18712090-Polyenes,
pubmed-meshheading:18712090-Polyporales,
pubmed-meshheading:18712090-Radioligand Assay,
pubmed-meshheading:18712090-Rats,
pubmed-meshheading:18712090-Sex Hormone-Binding Globulin,
pubmed-meshheading:18712090-Testosterone
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|
pubmed:articleTitle |
[Molecular characteristics of testosterone binding globulin and analysis of their regulation].
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|
pubmed:publicationType |
Journal Article,
English Abstract
|
