rdf:type |
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lifeskim:mentions |
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pubmed:issue |
16
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pubmed:dateCreated |
1991-9-18
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pubmed:abstractText |
In adult monkeys, peripheral nerve injuries induce dramatic examples of neural plasticity in somatosensory cortex. It has been suggested that a cortical distance limit exists and that the amount of plasticity that is possible after injury is constrained by this limit. We have investigated this possibility by depriving a relatively large expanse of cortex by transecting and ligating both the median and the ulnar nerves to the hand. Electrophysiological recording in cortical areas 3b and 1 in three adult squirrel monkeys no less than 2 months after nerve transection has revealed that cutaneous responsiveness is regained throughout the deprived cortex and that a roughly normal topographic order is reestablished for the reorganized cortex.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/1871112-1690224,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1871112-1843843,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1871112-2245335,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/1871112-497840,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/1871112-98537
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0027-8424
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6976-80
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
|
pubmed:year |
1991
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pubmed:articleTitle |
Large-scale functional reorganization in adult monkey cortex after peripheral nerve injury.
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pubmed:affiliation |
Department of Psychology, Vanderbilt University, Nashville, TN 37240.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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