Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2008-10-30
pubmed:abstractText
Genetic testing for BRCA1 and BRCA2 (BRCA1/2) mutations can provide important information for women who are concerned about their breast and ovarian cancer risks and need to make relevant prevention and medical management decisions. However, lifetime risks of breast cancer in individual BRCA1/2 mutation carriers have been confusing to apply in clinical decision-making. Published risk estimates vary significantly and are very dependent on the characteristics of the population under study. Recently, Begg and colleagues estimated cancer risks in a population-based study of BRCA1/2 mutation carriers. Here, we discuss the clinical decision-making implications of this research in the context of risk factors that may influence risk estimates in BRCA1/2 mutation carriers.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-10498392, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-11454686, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-12023993, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-12237282, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-14576434, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-15095307, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-16032702, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-16144894, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-16244359, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-16314625, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-16492929, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-16622123, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-17187672, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-17364225, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-17416765, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-17503428, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-17627006, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-17635951, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-17855685, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-17982329, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-17999359, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-18182601, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-18190724, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-18269778, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-18355772, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-7493024, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-7825587, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-8988179, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-9605646, http://linkedlifedata.com/resource/pubmed/commentcorrection/18710587-9634504
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1465-542X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
108
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Variation in breast cancer risk in BRCA1 and BRCA2 mutation carriers.
pubmed:affiliation
Center for Clinical Epidemiology and Biostatistics and Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA. rebbeck@mail.med.upenn.edu
pubmed:publicationType
Editorial