rdf:type |
|
lifeskim:mentions |
umls-concept:C0017296,
umls-concept:C0031928,
umls-concept:C0033414,
umls-concept:C0043240,
umls-concept:C0078058,
umls-concept:C0302600,
umls-concept:C0332854,
umls-concept:C0392752,
umls-concept:C0599779,
umls-concept:C1256770,
umls-concept:C2347946
|
pubmed:issue |
10
|
pubmed:dateCreated |
2008-9-22
|
pubmed:abstractText |
Anastomotic leak related to ischemia is a source of significant morbidity and mortality in gastrointestinal surgery. The aim of this study was to apply growth factor gene transfection for the purpose of up-regulating angiogenesis, increasing anastomotic strength, and ultimately preventing dehiscence.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
1873-4626
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
12
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1762-70; discussion 1771-2
|
pubmed:meshHeading |
pubmed-meshheading:18709424-Anastomosis, Surgical,
pubmed-meshheading:18709424-Animals,
pubmed-meshheading:18709424-Disease Models, Animal,
pubmed-meshheading:18709424-Esophagectomy,
pubmed-meshheading:18709424-Gastrectomy,
pubmed-meshheading:18709424-Gene Therapy,
pubmed-meshheading:18709424-Ischemia,
pubmed-meshheading:18709424-Neovascularization, Physiologic,
pubmed-meshheading:18709424-Opossums,
pubmed-meshheading:18709424-Pilot Projects,
pubmed-meshheading:18709424-Plasmids,
pubmed-meshheading:18709424-Surgical Wound Dehiscence,
pubmed-meshheading:18709424-Transfection,
pubmed-meshheading:18709424-Wound Healing
|
pubmed:year |
2008
|
pubmed:articleTitle |
VEGF gene therapy augments localized angiogenesis and promotes anastomotic wound healing: a pilot study in a clinically relevant animal model.
|
pubmed:affiliation |
Department of Surgery, Oregon Health & Science University, Portland, OR, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|