18709380

Source:http://linkedlifedata.com/resource/pubmed/id/18709380

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017337, umls-concept:C0078058, umls-concept:C0154830, umls-concept:C0205419, umls-concept:C0449258, umls-concept:C1256770
pubmed:issue	1
pubmed:dateCreated	2008-11-21
pubmed:abstractText	The development of diabetic retinopathy is associated with the duration of diabetes and HbA1c levels. However, the familial aggregation of diabetic retinopathy is consistent with genetic susceptibility. Recently, a -634C/G polymorphism in the vascular endothelial growth factor (VEGF) gene was shown to be associated with diabetic retinopathy. To clarify the contribution of the VEGF gene in the development of diabetic retinopathy we analyzed variants in this gene among 469 Japanese patients with type 2 diabetes.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8205248
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/VEGFA protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A
pubmed:status	MEDLINE
pubmed:month	Jan
pubmed:issn	1435-702X
pubmed:author	pubmed-author:FunatsuHideharuH, pubmed-author:IwamotoYasuhikoY, pubmed-author:IwasakiNaokoN, pubmed-author:KitanoShigehikoS, pubmed-author:NakamuraShinkoS
pubmed:issnType	Electronic
pubmed:volume	247
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	21-6
pubmed:meshHeading	pubmed-meshheading:18709380-Adult, pubmed-meshheading:18709380-Asian Continental Ancestry Group, pubmed-meshheading:18709380-Diabetes Mellitus, Type 2, pubmed-meshheading:18709380-Diabetic Retinopathy, pubmed-meshheading:18709380-Disease Progression, pubmed-meshheading:18709380-Female, pubmed-meshheading:18709380-Gene Frequency, pubmed-meshheading:18709380-Genetic Predisposition to Disease, pubmed-meshheading:18709380-Genetic Variation, pubmed-meshheading:18709380-Genotype, pubmed-meshheading:18709380-Humans, pubmed-meshheading:18709380-Japan, pubmed-meshheading:18709380-Male, pubmed-meshheading:18709380-Middle Aged, pubmed-meshheading:18709380-Polymorphism, Single Nucleotide, pubmed-meshheading:18709380-Risk Factors, pubmed-meshheading:18709380-Vascular Endothelial Growth Factor A, pubmed-meshheading:18709380-Vitreous Body
pubmed:year	2009
pubmed:articleTitle	Impact of variants in the VEGF gene on progression of proliferative diabetic retinopathy.
pubmed:affiliation	Department of Ophthalmology, Diabetes Center, Tokyo Women's Medical University, 8-1, Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan. marumo@silk.ocn.ne.jp
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't