|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0004238,
umls-concept:C0014442,
umls-concept:C0017262,
umls-concept:C0018792,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0026336,
umls-concept:C0145947,
umls-concept:C0165519,
umls-concept:C0185117,
umls-concept:C0678594,
umls-concept:C1280551,
umls-concept:C2911684
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|
pubmed:issue |
6
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|
pubmed:dateCreated |
2008-11-10
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|
pubmed:abstractText |
Matrix metalloproteinases and tissue inhibitors of metalloproteinases regulate extracellular matrix turnover in cardiac tissues. However, alteration of matrix metalloproteinases and tissue inhibitors of metalloproteinases during atrial fibrillation is unclear. This study aims to determine (a) the relationship between altered expressions of matrix metalloproteinases and tissue inhibitors of metalloproteinases and atrial structural remodeling; (b) the role of changes in the atrial angiotensin system and in calcium concentration; and (c) the effect of captopril on the expressions of matrix metalloproteinase-9/tissue inhibitors of metalloproteinase-1 and atrial structural remodeling.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1879-1336
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
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|
pubmed:volume |
17
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
399-409
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pubmed:meshHeading |
pubmed-meshheading:18706834-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:18706834-Animals,
pubmed-meshheading:18706834-Atrial Fibrillation,
pubmed-meshheading:18706834-Calcium,
pubmed-meshheading:18706834-Captopril,
pubmed-meshheading:18706834-Dogs,
pubmed-meshheading:18706834-Gene Expression,
pubmed-meshheading:18706834-Heart Atria,
pubmed-meshheading:18706834-Immunohistochemistry,
pubmed-meshheading:18706834-Matrix Metalloproteinase 9,
pubmed-meshheading:18706834-Peptidyl-Dipeptidase A,
pubmed-meshheading:18706834-Polymerase Chain Reaction,
pubmed-meshheading:18706834-RNA, Messenger,
pubmed-meshheading:18706834-Tissue Inhibitor of Metalloproteinase-1
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|
pubmed:articleTitle |
Matrix metalloproteinase-9/tissue inhibitors of metalloproteinase-1 expression and atrial structural remodeling in a dog model of atrial fibrillation: inhibition with angiotensin-converting enzyme.
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pubmed:affiliation |
Department of Cardiology, Qilu Hospital of Shandong University, Ji'nan 250012, PR China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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