rdf:type |
|
lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2008-9-24
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pubmed:abstractText |
Cancer cachexia is an important, negative prognostic marker that has been linked to systemic inflammation and cell death through unclear mechanisms. A key feature of cancer cachexia is loss of white adipose tissue (WAT) because of increased adipocyte lipolysis and possibly reduced lipid synthesis (lipogenesis). In this study, the authors investigated whether alterations in fat cell numbers, lipogenesis, or cytokine and/or leukocyte infiltration could account for some of the functional changes observed in WAT in cancer cachexia.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Oct
|
pubmed:issn |
0008-543X
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
113
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1695-704
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pubmed:meshHeading |
pubmed-meshheading:18704987-Adipocytes,
pubmed-meshheading:18704987-Adipose Tissue, White,
pubmed-meshheading:18704987-Aged,
pubmed-meshheading:18704987-Cachexia,
pubmed-meshheading:18704987-Cell Count,
pubmed-meshheading:18704987-Cell Death,
pubmed-meshheading:18704987-Cytokines,
pubmed-meshheading:18704987-Female,
pubmed-meshheading:18704987-Humans,
pubmed-meshheading:18704987-Inflammation,
pubmed-meshheading:18704987-Interleukin-6,
pubmed-meshheading:18704987-Lipogenesis,
pubmed-meshheading:18704987-Lipolysis,
pubmed-meshheading:18704987-Lymphocytes, Tumor-Infiltrating,
pubmed-meshheading:18704987-Male,
pubmed-meshheading:18704987-Middle Aged,
pubmed-meshheading:18704987-Neoplasms
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pubmed:year |
2008
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pubmed:articleTitle |
Lipolysis--not inflammation, cell death, or lipogenesis--is involved in adipose tissue loss in cancer cachexia.
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pubmed:affiliation |
Department of Medicine, Karolinska Institute at Karolinska University Hospital, Stockholm, Sweden. mikael.ryden@ki.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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