|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
2008-9-29
|
|
pubmed:abstractText |
To determine whether participants in the behavior enhances drug reduction of incontinence (BE-DRI) trial experienced reduction in the frequency of nocturia and/or nocturnal leakage during treatment with antimuscarinic phamacotherapy with or without additional behavioral therapy. We analyzed urinary diary data relating to nocturia and nocturnal incontinence before and after 8 weeks of study treatment in the BE-DRI trial, in which patients were randomly assigned to receive drug therapy with tolterodine tartrate extended-release capsules 4 mg alone or in combination with behavioral training. Chi-square tests assessed whether nocturia and nocturnal incontinence prevalence varied by treatment arm and paired t tests assessed the change in mean frequency of nocturia and nocturnal leakage. Among 305 women, 210 (69%) had an average of at least one nocturia episode at baseline. There were small but statistically significant differences (p < 0.001) in mean nocturia frequency and nocturnal incontinence frequency with both treatments after 8 weeks, but no significant difference between study treatment groups. Among these urge incontinent women, tolterodine with or without supervised behavioral therapy had little impact on either nocturic frequency or nocturnal incontinence.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:author |
|
|
pubmed:volume |
19
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1545-50
|
|
pubmed:dateRevised |
2011-8-18
|
|
pubmed:meshHeading |
pubmed-meshheading:18704249-Administration, Oral,
pubmed-meshheading:18704249-Behavior Therapy,
pubmed-meshheading:18704249-Benzhydryl Compounds,
pubmed-meshheading:18704249-Cholinergic Antagonists,
pubmed-meshheading:18704249-Cresols,
pubmed-meshheading:18704249-Delayed-Action Preparations,
pubmed-meshheading:18704249-Dose-Response Relationship, Drug,
pubmed-meshheading:18704249-Female,
pubmed-meshheading:18704249-Follow-Up Studies,
pubmed-meshheading:18704249-Humans,
pubmed-meshheading:18704249-Middle Aged,
pubmed-meshheading:18704249-Muscarinic Antagonists,
pubmed-meshheading:18704249-Nocturia,
pubmed-meshheading:18704249-Nocturnal Enuresis,
pubmed-meshheading:18704249-Phenylpropanolamine,
pubmed-meshheading:18704249-Prevalence,
pubmed-meshheading:18704249-Treatment Outcome,
pubmed-meshheading:18704249-United States,
pubmed-meshheading:18704249-Urodynamics
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Nocturia, nocturnal incontinence prevalence, and response to anticholinergic and behavioral therapy.
|
|
pubmed:affiliation |
Loyola University Medical Center, Maywood, IL 60153, USA. Mfitzg8@lumc.edu
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Multicenter Study,
Research Support, N.I.H., Extramural
|
