Linked Life Data

18702947

Source:http://linkedlifedata.com/resource/pubmed/id/18702947

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2008-8-15
pubmed:abstractText
Sex differences exist in the expression of different inflammation-sensitive biomarkers in relation to the metabolic syndrome (MetS). We have presently explored these differences in relation to commonly used inflammation-sensitive biomarkers including the high-sensitivity C-reactive protein (hs-CRP), quantitative fibrinogen, erythrocyte sedimentation rate (ESR), white blood cell count (WBCC), and absolute number of polymorphonuclear leukocytes. This is a cross-sectional analysis of a group of apparently healthy men (n = 5560) and women (n = 3049) in whom the results of the above-mentioned inflammation-sensitive biomarkers were analyzed in relation to the different components of MetS. The concentration of hs-CRP increased pari passu with the number of components of the MetS, the differences between the sexes being significant for any number of components of the MetS. Regarding fibrinogen, the influence of sex turned significant for waist only, similarly to the results of the ESR. None of these interactions were found to be significant for both the WBCC and the absolute number of polymorphonuclear leukocytes. Quantitative fibrinogen, ESR, WBCC, as well as the absolute number of polymorphonuclear leukocytes are not sensitive enough to reveal the potential sex differences in relation to the various components of the MetS and the expression of the low-grade inflammation. High-sensitivity CRP does have the capability to reveal these differences.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1532-8600
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1221-6
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Exploring the usefulness of inflammation-sensitive biomarkers to reveal potential sex differences in relation to low-grade inflammation in individuals with the metabolic syndrome.
pubmed:affiliation
Department of Medicine D, Tel Aviv Sourasky Medical Center, 64239 Tel Aviv, Israel.
pubmed:publicationType
Journal Article