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rdf:type |
|
|
lifeskim:mentions |
|
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pubmed:issue |
4
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pubmed:dateCreated |
2008-8-15
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|
pubmed:abstractText |
Vascular endothelial growth factor (VEGF), a pleiotropic polypeptide that mediates endothelial cell-specific responses such as induction of angiogenesis and vascular leakage, is hyperproduced in a variety of inflammatory disorders. In asthma, VEGF hyperproduction promotes mucosal edema by enhancing vascular leakage. However, in allergic rhinitis, details of the pathophysiological importance remain unclear. This study was designed to investigate and discuss the pathophysiological significance of VEGF in nasal secretions from perennial allergic rhinitis sufferers.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1050-6586
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
22
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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|
pubmed:pagination |
365-70
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pubmed:meshHeading |
pubmed-meshheading:18702899-Adult,
pubmed-meshheading:18702899-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:18702899-Female,
pubmed-meshheading:18702899-Follow-Up Studies,
pubmed-meshheading:18702899-Gene Expression,
pubmed-meshheading:18702899-Humans,
pubmed-meshheading:18702899-Immunohistochemistry,
pubmed-meshheading:18702899-Male,
pubmed-meshheading:18702899-Middle Aged,
pubmed-meshheading:18702899-Nasal Lavage Fluid,
pubmed-meshheading:18702899-Nasal Mucosa,
pubmed-meshheading:18702899-Nasal Provocation Tests,
pubmed-meshheading:18702899-RNA, Messenger,
pubmed-meshheading:18702899-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18702899-Rhinitis, Allergic, Perennial,
pubmed-meshheading:18702899-Severity of Illness Index,
pubmed-meshheading:18702899-Vascular Endothelial Growth Factor A
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pubmed:articleTitle |
Vascular endothelial growth factor produced in nasal glands of perennial allergic rhinitis.
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|
pubmed:affiliation |
Department of Otolaryngology, Head and Neck Surgery, Field of Sensory Organology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan. shoji@m2.kufm.kagoshima-u.ac.jp
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
