Linked Life Data

18701924

Source:http://linkedlifedata.com/resource/pubmed/id/18701924

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2008-12-16
pubmed:abstractText
We examined 55 consecutive patients successfully treated with primary percutaneous coronary intervention (PCI) for a first acute myocardial infarction with left ventricular (LV) systolic dysfunction. In all patients we performed echocardiographic examination, dosage of plasma brain natriuretic peptide, serum carboxy-terminal propeptide and telopeptide of procollagen type I and amino-terminal propeptide of procollagen type III at days 1 and 3, and at 1 and 6 months after index infarction. The hypertensive patients (group 1; n=30) differed for higher baseline blood pressure (133+/-4 mm Hg vs 118+/-4 mm Hg; P=0.03), greater LV mass index (108+/-5 vs 94+/-4 g m(-2), P=0.03) and lower mitral E/A wave peak (0.8+/-0.06 vs 1.1+/-0.12, P=0.02) with respect to non-hypertensive patients (group 2; n=25). From day 1 to month 6 carboxy-terminal propeptide of procollagen type I and amino-terminal propeptide of procollagen type III increased (P<0.005 and P<0.05, respectively) in both groups, whereas carboxy-terminal telopeptide of procollagen type I increased from day 1 to day 3 (P<0.01 in both groups, respectively) and then decreased from day 3 to month 6 (P<0.01 and P<0.05 in both groups, respectively). From day 1, brain natriuretic peptide decreased in both groups (P<0.005). There was no significant difference between the two groups in values of procollagens and natriuretic peptide. Finally, LV diastolic volume and function at 6 months were similar in the two groups. Thus, in patients with reperfused acute myocardial infarction and LV dysfunction, antecedent hypertension was not associated with a different pattern of serum procollagen release and ventricular remodelling at 6 months of follow-up.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0950-9240
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
40-7
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:18701924-Adrenergic beta-Antagonists, pubmed-meshheading:18701924-Aged, pubmed-meshheading:18701924-Angiography, pubmed-meshheading:18701924-Collagen Type I, pubmed-meshheading:18701924-Collagen Type III, pubmed-meshheading:18701924-Echocardiography, pubmed-meshheading:18701924-Female, pubmed-meshheading:18701924-Follow-Up Studies, pubmed-meshheading:18701924-Humans, pubmed-meshheading:18701924-Hypertension, pubmed-meshheading:18701924-Male, pubmed-meshheading:18701924-Middle Aged, pubmed-meshheading:18701924-Myocardial Infarction, pubmed-meshheading:18701924-Myocardial Reperfusion, pubmed-meshheading:18701924-Natriuretic Peptide, Brain, pubmed-meshheading:18701924-Peptide Fragments, pubmed-meshheading:18701924-Peptides, pubmed-meshheading:18701924-Procollagen, pubmed-meshheading:18701924-Time Factors, pubmed-meshheading:18701924-Ventricular Dysfunction, Left, pubmed-meshheading:18701924-Ventricular Remodeling
pubmed:year
2009
pubmed:articleTitle
Time course of serum collagen types I and III metabolism products after reperfused acute myocardial infarction in patients with and without systemic hypertension.
pubmed:affiliation
Division of Cardiology, Careggi Hospital, Florence, Italy. giampaolo.cerisano@tin.it
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't