Source:http://linkedlifedata.com/resource/pubmed/id/18698131
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-4
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pubmed:dateCreated |
2008-12-9
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pubmed:abstractText |
The avian eggshell primarily consists of calcium carbonate mineral (calcite) and matrix proteins. Here we review matrix-mineral relationships in the eggshell at the ultrastructural level using scanning and transmission electron microscopy, and describe the distribution of osteopontin (OPN) as determined by colloidal gold immunolabeling for OPN. A rich protein network integrated within the calcitic structure of the eggshell shows variable, region-specific organization that included layered fibrous planar sheets of matrix, thin filamentous threads, thin film-like surface coatings, vesicular structures and isolated proteins residing on cleaved {104} crystallographic faces of the eggshell calcite. Except for the vesicular structures, these matrix structures all immunolabeled strongly for OPN. Given the potent mineralization- inhibiting function of OPN, we discuss how this protein might regulate eggshell growth rate and inhibit calcification at specific compartmental boundaries to provide eggshell form.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1422-6421
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2008 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
189
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
38-43
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pubmed:meshHeading |
pubmed-meshheading:18698131-Animals,
pubmed-meshheading:18698131-Chickens,
pubmed-meshheading:18698131-Egg Shell,
pubmed-meshheading:18698131-Epithelial Cells,
pubmed-meshheading:18698131-Extracellular Matrix,
pubmed-meshheading:18698131-Membranes,
pubmed-meshheading:18698131-Minerals,
pubmed-meshheading:18698131-Osteopontin
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pubmed:year |
2009
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pubmed:articleTitle |
Avian eggshell structure and osteopontin.
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pubmed:affiliation |
Faculty of Dentistry, McGill University, Montreal, Que., Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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