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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1991-9-18
|
| pubmed:abstractText |
1. The electrolyte transport capacities of the porcine placenta and fetal membranes (amnion, chorion, and allantois) during gestation (47-112 days) were assessed in vitro and in the absence of electrochemical, osmotic, or hydrostatic driving forces. Net transmural transport of 22Na and 36Cl across sections of porcine allantochorion-endometrium (ALCE), amniochorion-endometrium (AMCE), and allantoamnion (AA) mounted in Ussing chambers could not be detected at any stage of gestation. 2. These tissues were characterised throughout gestation by low electrical potential difference (PD; less than 5 mV, fetal side positive with respect to maternal side) and short circuit current (SCC; less than 16 microA.cm-2) which were amiloride and iodoacetate sensitive. 3. A periparturitent reversal in the polarity of PD to fetal side negative and a change in the direction of the SCC was observed in tissues obtained from sows (n = 3) at 111-112 day gestation. These changes were accompanied by a 73% increase in electrical resistance (R) and a 2-10-fold decrease in the permeability of tissues to Na and Cl. 4. Morphological studies revealed a decrease in the thickness of allantoamnion and a decrease in the height of epithelia from ALCE, AMCE, and AA during gestation, indicating a decrease in activity. These morphological changes only partly explained the pre-term electrophysiological changes in these tissues.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0174-1578
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
161
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
189-98
|
| pubmed:dateRevised |
2009-6-8
|
| pubmed:meshHeading |
pubmed-meshheading:1869696-Animals,
pubmed-meshheading:1869696-Biological Transport,
pubmed-meshheading:1869696-Cell Membrane,
pubmed-meshheading:1869696-Cell Membrane Permeability,
pubmed-meshheading:1869696-Chlorine,
pubmed-meshheading:1869696-Electric Conductivity,
pubmed-meshheading:1869696-Electrolytes,
pubmed-meshheading:1869696-Extraembryonic Membranes,
pubmed-meshheading:1869696-Female,
pubmed-meshheading:1869696-Fetus,
pubmed-meshheading:1869696-Maternal-Fetal Exchange,
pubmed-meshheading:1869696-Membrane Potentials,
pubmed-meshheading:1869696-Placenta,
pubmed-meshheading:1869696-Pregnancy,
pubmed-meshheading:1869696-Pregnancy, Animal,
pubmed-meshheading:1869696-Radioisotopes,
pubmed-meshheading:1869696-Sodium Radioisotopes,
pubmed-meshheading:1869696-Swine
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
Gestational changes in electrolyte transport, electrical activity, and permeability of the porcine placenta.
|
| pubmed:affiliation |
Department of Physiology, Monash University, Clayton, Australia.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|