| pubmed-article:18696151 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18696151 | lifeskim:mentions | umls-concept:C0027651 | lld:lifeskim |
| pubmed-article:18696151 | lifeskim:mentions | umls-concept:C0034493 | lld:lifeskim |
| pubmed-article:18696151 | lifeskim:mentions | umls-concept:C0021102 | lld:lifeskim |
| pubmed-article:18696151 | lifeskim:mentions | umls-concept:C1704922 | lld:lifeskim |
| pubmed-article:18696151 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:18696151 | lifeskim:mentions | umls-concept:C0392747 | lld:lifeskim |
| pubmed-article:18696151 | lifeskim:mentions | umls-concept:C0850292 | lld:lifeskim |
| pubmed-article:18696151 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:18696151 | pubmed:dateCreated | 2009-2-9 | lld:pubmed |
| pubmed-article:18696151 | pubmed:abstractText | The objective of this study was to evaluate the early changes after radiofrequency ablation (RFA) in VX2 rabbit tumors implanted into the back muscles by diffusion-weighted magnetic resonance (MR) imaging and (18)F-2-fluoro-2-deoxy-D-glucose positron emission tomography ((18)F-FDG PET). Percutaneous CT-guided RFA was conducted in seven rabbits with implanted VX2 tumors. VX2 tumors on the other side were untreated and served as the control. MR imaging was performed with a clinical 1.5-T instrument 2 days after RFA, and FDG-PET, using a high-resolution PET scanner for small animals, was obtained 3 days after the procedure. The mean apparent diffusion coefficient (ADC) values and radioactivity count of untreated and ablated tumors were calculated. Untreated VX2 tumors showed hyperintensity on T1-, T2-, and diffusion-weighted MR images, ring-enhanced on contrast-enhanced T1-weighted imaging, and ring-shaped FDG accumulation on FDG-PET. Ablated VX2 tumors showed slight hyperintensity on T1-, T2-, and diffusion-weighed images, slight enhancement on contrast-enhanced T1-weighted images, and low accumulation on FDG-PET. The ADC value of ablated VX2 tumors (1.52 +/- 0.24 x 10(-3) mm(2)/s) was significantly higher than that of untreated tumors (1.09 +/- 0.12 x 10(-3); p < 0.05). The tumor/muscle ratio of ablated tumors (0.5 +/- 0.3) was significantly lower than that of untreated tumors (11.6 +/- 3.2; p < 0.05). Histopathological examination confirmed the lack of viable tumor cells in the ablated lesions. The results indicate that both ADC value and FDG-PET are potentially useful markers for monitoring the early effects of RFA. | lld:pubmed |
| pubmed-article:18696151 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18696151 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18696151 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18696151 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18696151 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18696151 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18696151 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18696151 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:18696151 | pubmed:issn | 1432-086X | lld:pubmed |
| pubmed-article:18696151 | pubmed:author | pubmed-author:WatanabeYasuy... | lld:pubmed |
| pubmed-article:18696151 | pubmed:author | pubmed-author:NakamuraKenji... | lld:pubmed |
| pubmed-article:18696151 | pubmed:author | pubmed-author:InoueYuichiY | lld:pubmed |
| pubmed-article:18696151 | pubmed:author | pubmed-author:MatsuokaToshi... | lld:pubmed |
| pubmed-article:18696151 | pubmed:author | pubmed-author:WadaYasuhiroY | lld:pubmed |
| pubmed-article:18696151 | pubmed:author | pubmed-author:OkumaTomohisa... | lld:pubmed |
| pubmed-article:18696151 | pubmed:author | pubmed-author:OhiraTomohiro... | lld:pubmed |
| pubmed-article:18696151 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18696151 | pubmed:volume | 32 | lld:pubmed |
| pubmed-article:18696151 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18696151 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18696151 | pubmed:pagination | 114-20 | lld:pubmed |
| pubmed-article:18696151 | pubmed:meshHeading | pubmed-meshheading:18696151... | lld:pubmed |
| pubmed-article:18696151 | pubmed:meshHeading | pubmed-meshheading:18696151... | lld:pubmed |
| pubmed-article:18696151 | pubmed:meshHeading | pubmed-meshheading:18696151... | lld:pubmed |
| pubmed-article:18696151 | pubmed:meshHeading | pubmed-meshheading:18696151... | lld:pubmed |
| pubmed-article:18696151 | pubmed:meshHeading | pubmed-meshheading:18696151... | lld:pubmed |
| pubmed-article:18696151 | pubmed:meshHeading | pubmed-meshheading:18696151... | lld:pubmed |
| pubmed-article:18696151 | pubmed:meshHeading | pubmed-meshheading:18696151... | lld:pubmed |
| pubmed-article:18696151 | pubmed:meshHeading | pubmed-meshheading:18696151... | lld:pubmed |
| pubmed-article:18696151 | pubmed:meshHeading | pubmed-meshheading:18696151... | lld:pubmed |
| pubmed-article:18696151 | pubmed:meshHeading | pubmed-meshheading:18696151... | lld:pubmed |
| pubmed-article:18696151 | pubmed:meshHeading | pubmed-meshheading:18696151... | lld:pubmed |
| pubmed-article:18696151 | pubmed:meshHeading | pubmed-meshheading:18696151... | lld:pubmed |
| pubmed-article:18696151 | pubmed:meshHeading | pubmed-meshheading:18696151... | lld:pubmed |
| pubmed-article:18696151 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:18696151 | pubmed:articleTitle | FDG-MicroPET and diffusion-weighted MR image evaluation of early changes after radiofrequency ablation in implanted VX2 tumors in rabbits. | lld:pubmed |
| pubmed-article:18696151 | pubmed:affiliation | Department of Radiology, Osaka City University Graduate School of Medicine, Osaka, Japan. | lld:pubmed |
| pubmed-article:18696151 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18696151 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18696151 | lld:pubmed |
