Linked Life Data

18692715

Source:http://linkedlifedata.com/resource/pubmed/id/18692715

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9637
pubmed:dateCreated
2008-8-11
pubmed:abstractText
Primary immunodeficiencies comprise many diseases caused by genetic defects primarily affecting the immune system. About 150 such diseases have been identified with more than 120 associated genetic defects. Although primary immunodeficiencies are quite rare in incidence, the prevalence can range from one in 500 to one in 500 000 in the general population, depending on the diagnostic skills and medical resources available in different countries. Common variable immunodeficiency (CVID) is the primary immunodeficiency most commonly encountered in clinical practice, and appropriate diagnosis and management of patients will have a significant effect on morbidity and mortality as well as financial aspects of health care. Advances in diagnostic laboratory methods, including B-cell subset analysis and genetic testing, coupled with new insights into the molecular basis of immune dysfunction in some patients with CVID, have enabled advances in the clinical classification of this heterogeneous disease.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1474-547X
pubmed:author
pubmed:issnType
Electronic
pubmed:day
9
pubmed:volume
372
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
489-502
pubmed:dateRevised
2008-12-16
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Common variable immunodeficiency: a new look at an old disease.
pubmed:affiliation
Division of Allergic Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
pubmed:publicationType
Journal Article, Review