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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2008-12-16
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pubmed:abstractText |
Uterine benign leiomyomas result from proliferation of a single smooth-muscle cell and their growth is affected by steroid hormones via steroid hormone receptors. This investigation analyzed the +331G/A and the V600L single nucleotide polymorphisms in the progesterone receptor, and correlated their incidence with clinical and tumor parameters as well as disease risk.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1097-6868
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
199
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
648.e1-9
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pubmed:meshHeading |
pubmed-meshheading:18691687-Adult,
pubmed-meshheading:18691687-Alleles,
pubmed-meshheading:18691687-Case-Control Studies,
pubmed-meshheading:18691687-Female,
pubmed-meshheading:18691687-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:18691687-Genetic Predisposition to Disease,
pubmed-meshheading:18691687-Genotype,
pubmed-meshheading:18691687-Humans,
pubmed-meshheading:18691687-Incidence,
pubmed-meshheading:18691687-Leiomyoma,
pubmed-meshheading:18691687-Linear Models,
pubmed-meshheading:18691687-Middle Aged,
pubmed-meshheading:18691687-Polymorphism, Single Nucleotide,
pubmed-meshheading:18691687-Probability,
pubmed-meshheading:18691687-Receptors, Progesterone,
pubmed-meshheading:18691687-Reference Values,
pubmed-meshheading:18691687-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18691687-Risk Assessment,
pubmed-meshheading:18691687-Sensitivity and Specificity,
pubmed-meshheading:18691687-Uterine Neoplasms
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pubmed:year |
2008
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pubmed:articleTitle |
Single nucleotide polymorphisms in the progesterone receptor gene and association with uterine leiomyoma tumor characteristics and disease risk.
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pubmed:affiliation |
Department of Gynaecology and Obstetrics, University-Clinic Erlangen, Laboratory for Molecular Medicine, Erlangen, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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