Linked Life Data

18691499

Source:http://linkedlifedata.com/resource/pubmed/id/18691499

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2008-8-11
pubmed:abstractText
Tissue factor (TF) is the major physiological initiator of blood coagulation. It exists as an integral membrane protein that upon injury to the blood vessel becomes exposed to the blood stream and initiates a series of enzymatic reactions that cause blood to clot. TF is also found within circulating blood cells, requiring specific signaling events to promote its expression. In this review we will discuss current controversies concerning the structure-activity relationships of TF and contributions of TF to the hemostatic process, the potential roles of intravascular TF, including non-cell-bound TF and cell-expressed TF and the overall relationship between TF function and hemorrhage control.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0049-3848
pubmed:author
pubmed:issnType
Print
pubmed:volume
122 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S42-6
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Tissue factor activity and function in blood coagulation.
pubmed:affiliation
Department of Biochemistry, University of Vermont, Burlington, VT, USA. sbutenas@uvm.edu
pubmed:publicationType
Journal Article, Review, Research Support, N.I.H., Extramural