pubmed-article:1868873 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1868873 | lifeskim:mentions | umls-concept:C0019682 | lld:lifeskim |
pubmed-article:1868873 | lifeskim:mentions | umls-concept:C0021311 | lld:lifeskim |
pubmed-article:1868873 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:1868873 | lifeskim:mentions | umls-concept:C0242245 | lld:lifeskim |
pubmed-article:1868873 | lifeskim:mentions | umls-concept:C0204727 | lld:lifeskim |
pubmed-article:1868873 | lifeskim:mentions | umls-concept:C0205409 | lld:lifeskim |
pubmed-article:1868873 | lifeskim:mentions | umls-concept:C0205307 | lld:lifeskim |
pubmed-article:1868873 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
pubmed-article:1868873 | pubmed:issue | 8 | lld:pubmed |
pubmed-article:1868873 | pubmed:dateCreated | 1991-9-13 | lld:pubmed |
pubmed-article:1868873 | pubmed:abstractText | Immunohistological and electron microscopy studies of lymph nodes from patients infected with the human immunodeficiency virus 1 (HIV-1) demonstrated that follicular dendritic cells (FDC), the antigen-presenting cells of the B cell system, contain and may produce the virus. To elucidate the mode of infection of FDC with HIV-1 in vitro we developed an improved method for the preparation of single-cell suspensions of viable FDC with high purity (greater than 90% FDC). These isolated FDC were subjected to human T cell leukemia virus IIIB infection, which was monitored after 4 days in culture using the polymerase chain reaction. We were able to demonstrate that normal human FDC are highly susceptible to infection by HIV-1. Inhibition experiments with the monoclonal antibody OKT4a demonstrate that this infection is independent of the CD4 molecule. | lld:pubmed |
pubmed-article:1868873 | pubmed:language | eng | lld:pubmed |
pubmed-article:1868873 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1868873 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:1868873 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1868873 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1868873 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1868873 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1868873 | pubmed:month | Aug | lld:pubmed |
pubmed-article:1868873 | pubmed:issn | 0014-2980 | lld:pubmed |
pubmed-article:1868873 | pubmed:author | pubmed-author:SchmitzHH | lld:pubmed |
pubmed-article:1868873 | pubmed:author | pubmed-author:GATEM AMA | lld:pubmed |
pubmed-article:1868873 | pubmed:author | pubmed-author:ErnstMM | lld:pubmed |
pubmed-article:1868873 | pubmed:author | pubmed-author:GerdesJJ | lld:pubmed |
pubmed-article:1868873 | pubmed:author | pubmed-author:FennerTT | lld:pubmed |
pubmed-article:1868873 | pubmed:author | pubmed-author:ZimmerJ PJP | lld:pubmed |
pubmed-article:1868873 | pubmed:author | pubmed-author:StahmerII | lld:pubmed |
pubmed-article:1868873 | pubmed:author | pubmed-author:FinnernRR | lld:pubmed |
pubmed-article:1868873 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1868873 | pubmed:volume | 21 | lld:pubmed |
pubmed-article:1868873 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1868873 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1868873 | pubmed:pagination | 1873-8 | lld:pubmed |
pubmed-article:1868873 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:1868873 | pubmed:meshHeading | pubmed-meshheading:1868873-... | lld:pubmed |
pubmed-article:1868873 | pubmed:meshHeading | pubmed-meshheading:1868873-... | lld:pubmed |
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pubmed-article:1868873 | pubmed:meshHeading | pubmed-meshheading:1868873-... | lld:pubmed |
pubmed-article:1868873 | pubmed:meshHeading | pubmed-meshheading:1868873-... | lld:pubmed |
pubmed-article:1868873 | pubmed:year | 1991 | lld:pubmed |
pubmed-article:1868873 | pubmed:articleTitle | Isolation of normal human follicular dendritic cells and CD4-independent in vitro infection by human immunodeficiency virus (HIV-1). | lld:pubmed |
pubmed-article:1868873 | pubmed:affiliation | Forschungsinstitut Borstel, Department of Immunology and Cell Biology, FRG. | lld:pubmed |
pubmed-article:1868873 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:1868873 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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