Dendritic Cells, Follicular

Source:http://linkedlifedata.com/resource/umls/id/C0242245

MSH: Non-hematopoietic cells, with extensive dendritic processes, found in the primary and secondary follicles of lymphoid tissue (the B cell zones). They are different from conventional DENDRITIC CELLS associated with T-CELLS. They are derived from MESENCHYMAL STEM CELLS and are negative for class II MHC antigen and do not process or present antigen like the conventional dendritic cells do. Instead, follicular dendritic cells have FC RECEPTORS and C3B RECEPTORS that hold antigen in the form of ANTIGEN-ANTIBODY COMPLEXES on their surfaces for long periods for recognition by B-CELLS.,NCI: Antigen Presenting Cells (APCs) located in the follicles of secondary lymphoid organs. These dendritic cells are unique because of their location, primarily in lymphoid follicles, and because of their function in retaining antigen molecules for extended periods of time and serving as APCs for B cells.

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