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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-11-5
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pubmed:abstractText |
Perifosine is an orally active alkylphospholipid analog, which has shown anti-tumor activity in a variety of cancers by inhibition of AKT phosphorylation. The objective of the current study was to evaluate its efficacy in in vitro models of human endometrial cancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0301-2115
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pubmed:author |
pubmed-author:DietlJohannesJ,
pubmed-author:DombrowskiYvonneY,
pubmed-author:EngelJörg BJB,
pubmed-author:GrunewaldThomas GTG,
pubmed-author:HäuslerSebastianS,
pubmed-author:HonigArndA,
pubmed-author:KrockenbergerMathiasM,
pubmed-author:RiegerLorenzL,
pubmed-author:SchönhalsTanjaT,
pubmed-author:WeidlerClaudiaC,
pubmed-author:WischhusenJörgJ
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pubmed:issnType |
Print
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pubmed:volume |
141
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
64-9
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:18687514-Antineoplastic Agents,
pubmed-meshheading:18687514-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:18687514-Apoptosis,
pubmed-meshheading:18687514-Cell Line, Tumor,
pubmed-meshheading:18687514-Cisplatin,
pubmed-meshheading:18687514-Endometrial Neoplasms,
pubmed-meshheading:18687514-Female,
pubmed-meshheading:18687514-Humans,
pubmed-meshheading:18687514-Phosphorylation,
pubmed-meshheading:18687514-Phosphorylcholine,
pubmed-meshheading:18687514-Proto-Oncogene Proteins c-akt
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pubmed:year |
2008
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pubmed:articleTitle |
Perifosine inhibits growth of human experimental endometrial cancers by blockade of AKT phosphorylation.
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pubmed:affiliation |
Universitätsfrauenklinik Würzburg, Germany. joergbengel@hotmail.com
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pubmed:publicationType |
Journal Article
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