Linked Life Data

18687037

Source:http://linkedlifedata.com/resource/pubmed/id/18687037

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2008-8-25
pubmed:abstractText
The objective of this study was to evaluate the relevant sensory spinal pathways involved in conveying conduction of electrical perceptual threshold (EPT). In 34 individuals with cervical spinal cord injury (SCI) and eight healthy control subjects, combined EPT and electrical pain perception (EPP), and dermatomal somatosensory evoked potentials (dSSEP) from cervical dermatomes were examined. Stimulation intensities for EPT were recorded to determine quantitative sensory perception and related neurophysiological dSSEP interpretation of posterior spinal cord conduction based on onset latency and waveform configuration. The preservation of EPP in dermatomes was examined relative to EPT to dissociate the involvement of the posterior (dorsal horn and ascending dorsal column) and anterior (decussating and ascending spinothalamic fibers) spinal cord according to different nerve fiber recruitment in the periphery. Pathological EPT values were significantly (p < 0.05) accurate at predicting pathological and abolished dSSEP recordings (>80%), and the mean EPT of pathological and abolished dSSEPs was significantly (p < 0.05) increased compared to non-affected and control dSSEPs. dSSEPs demonstrated normal early onset latency at perceptually low stimulation intensities (<2.5 mA), and selectively absent EPP was dissociated from preserved EPT and/or dSSEP in 22.2% of dermatomes with incomplete sensory deficit. The relationship between EPT and dSSEP interpretation, dSSEP early onset latency and perceptual stimulation intensity, and the dissociation of EPT from EPP suggests that EPT is conducted within the posterior spinal cord. The combination of EPT and EPP with dSSEPs provides reliable quantitative sensory information to assess the segmental integrity of the posterior and anterior spinal cord, and may improve the sensitivity to monitor changes in sensory function after SCI.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0897-7151
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1019-26
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Assessment of posterior spinal cord function with electrical perception threshold in spinal cord injury.
pubmed:affiliation
The International Collaboration On Repair Discoveries (ICORD) and Division of Neurology, Vancouver, British Columbia, Canada. jkramer@icord.org
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't