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rdf:type |
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lifeskim:mentions |
umls-concept:C0018850,
umls-concept:C0019144,
umls-concept:C0034693,
umls-concept:C0061231,
umls-concept:C0151763,
umls-concept:C0205178,
umls-concept:C0205263,
umls-concept:C0282553,
umls-concept:C0301625,
umls-concept:C0522501,
umls-concept:C0812445,
umls-concept:C1292733,
umls-concept:C1705593
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pubmed:issue |
1
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pubmed:dateCreated |
2008-12-19
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pubmed:abstractText |
Acute liver failure after massive hepatectomy remains a challenging problem. In this study, using a microarray designed to monitor the side effects of drugs, we examined changes in gene expression in the remnant liver during the 24 h after hepatectomy and the effects of a nontoxic heat shock protein (HSP) 70 inducer, geranylgeranylacetone (GGA), after 90% hepatectomy in rats.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1873-4626
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
66-73
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pubmed:meshHeading |
pubmed-meshheading:18683011-Animals,
pubmed-meshheading:18683011-Anti-Ulcer Agents,
pubmed-meshheading:18683011-Autoradiography,
pubmed-meshheading:18683011-Blotting, Western,
pubmed-meshheading:18683011-Chemokine CXCL1,
pubmed-meshheading:18683011-Disease Models, Animal,
pubmed-meshheading:18683011-Diterpenes,
pubmed-meshheading:18683011-Dose-Response Relationship, Drug,
pubmed-meshheading:18683011-Gene Expression,
pubmed-meshheading:18683011-HSP70 Heat-Shock Proteins,
pubmed-meshheading:18683011-Hepatectomy,
pubmed-meshheading:18683011-Liver Failure, Acute,
pubmed-meshheading:18683011-Male,
pubmed-meshheading:18683011-Microarray Analysis,
pubmed-meshheading:18683011-RNA,
pubmed-meshheading:18683011-Rats,
pubmed-meshheading:18683011-Rats, Wistar,
pubmed-meshheading:18683011-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2009
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pubmed:articleTitle |
Geranylgeranylacetone prevents acute liver damage after massive hepatectomy in rats through suppression of a CXC chemokine GRO1 and induction of heat shock proteins.
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pubmed:affiliation |
Department of Digestive and Pediatric Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
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