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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2008-9-9
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pubmed:abstractText |
In the course of a meningococcal infection, invasive and severe disease occurs in a restricted number of individuals. The predominant mechanism of death in case of meningococcal septic shock is circulatory failure. Inotropic requirements between patients vary widely. We investigated whether polymorphisms in genes regulating the hemodynamic response influence the amount of inotropics required or the susceptibility to severe meningococcal disease.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1529-7535
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
517-23
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pubmed:meshHeading |
pubmed-meshheading:18679149-Adult,
pubmed-meshheading:18679149-Calmodulin-Binding Proteins,
pubmed-meshheading:18679149-Case-Control Studies,
pubmed-meshheading:18679149-Child,
pubmed-meshheading:18679149-Child, Preschool,
pubmed-meshheading:18679149-Female,
pubmed-meshheading:18679149-Gene Frequency,
pubmed-meshheading:18679149-Genotype,
pubmed-meshheading:18679149-Homeostasis,
pubmed-meshheading:18679149-Humans,
pubmed-meshheading:18679149-Infant,
pubmed-meshheading:18679149-Intensive Care Units, Pediatric,
pubmed-meshheading:18679149-Male,
pubmed-meshheading:18679149-Meningococcal Infections,
pubmed-meshheading:18679149-Middle Aged,
pubmed-meshheading:18679149-Polymorphism, Single Nucleotide,
pubmed-meshheading:18679149-Receptors, Adrenergic, beta-1,
pubmed-meshheading:18679149-Retrospective Studies
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pubmed:year |
2008
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pubmed:articleTitle |
Single nucleotide polymorphisms in genes of circulatory homeostasis in surviving pediatric intensive care patients with meningococcal infection.
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pubmed:affiliation |
Pediatric Intensive Care Unit, The Emma Children's hospital/Academic Medical Center, Amsterdam, Netherlands. h.e.wiersma@amc.uva.nl
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pubmed:publicationType |
Journal Article
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