Source:http://linkedlifedata.com/resource/pubmed/id/18678419
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2009-8-25
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pubmed:abstractText |
We examined if a loss-of-function polymorphism in the P2X(7) receptor (1513C) corresponded with circulating interleukin(IL)-18 concentrations in heart failure (HF) patients. IL-18 values were significantly elevated in HF subjects compared to healthy control subjects. No association was seen between the polymorphism and IL-18 concentrations in HF patients. In HF patients, IL-18 values had an inverse relationship with ejection fraction, mean arterial pressure and body mass index, while high IL-18 concentrations were associated with increased mortality.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1874-1754
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
11
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pubmed:volume |
137
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
81-3
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:18678419-Female,
pubmed-meshheading:18678419-Heart Failure,
pubmed-meshheading:18678419-Humans,
pubmed-meshheading:18678419-Interleukin-18,
pubmed-meshheading:18678419-Male,
pubmed-meshheading:18678419-Middle Aged,
pubmed-meshheading:18678419-Pilot Projects,
pubmed-meshheading:18678419-Polymorphism, Genetic,
pubmed-meshheading:18678419-Receptors, Purinergic P2,
pubmed-meshheading:18678419-Receptors, Purinergic P2X7
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pubmed:year |
2009
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pubmed:articleTitle |
Circulating interleukin-18 concentrations and a loss-of-function P2X7 polymorphism in heart failure.
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pubmed:publicationType |
Letter,
Comparative Study
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