|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007634,
umls-concept:C0033684,
umls-concept:C0040649,
umls-concept:C0086418,
umls-concept:C0205314,
umls-concept:C0441655,
umls-concept:C0679622,
umls-concept:C0851285,
umls-concept:C0851287,
umls-concept:C1299003,
umls-concept:C1414668
|
|
pubmed:issue |
12
|
|
pubmed:dateCreated |
2008-11-27
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|
pubmed:abstractText |
Mutations in the human forkhead box C1 gene (FOXC1) cause Axenfeld-Rieger (AR) malformations, often leading to glaucoma. Understanding the function of FOXC1 necessitates characterizing the proteins that interact with FOXC1. This study was undertaken to isolate FOXC1-interacting proteins and determine their effects on FOXC1.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
1552-5783
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
49
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
5243-9
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pubmed:meshHeading |
pubmed-meshheading:18676636-Animals,
pubmed-meshheading:18676636-Anterior Eye Segment,
pubmed-meshheading:18676636-COS Cells,
pubmed-meshheading:18676636-Carrier Proteins,
pubmed-meshheading:18676636-Cercopithecus aethiops,
pubmed-meshheading:18676636-DNA-Binding Proteins,
pubmed-meshheading:18676636-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:18676636-Electrophoretic Mobility Shift Assay,
pubmed-meshheading:18676636-Eye Abnormalities,
pubmed-meshheading:18676636-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:18676636-Forkhead Transcription Factors,
pubmed-meshheading:18676636-Glaucoma,
pubmed-meshheading:18676636-HeLa Cells,
pubmed-meshheading:18676636-Humans,
pubmed-meshheading:18676636-Immunoprecipitation,
pubmed-meshheading:18676636-Mitochondrial Proteins,
pubmed-meshheading:18676636-Plasmids,
pubmed-meshheading:18676636-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:18676636-Trabecular Meshwork,
pubmed-meshheading:18676636-Transcriptional Activation,
pubmed-meshheading:18676636-Transfection,
pubmed-meshheading:18676636-Two-Hybrid System Techniques
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|
pubmed:year |
2008
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|
pubmed:articleTitle |
Human p32 is a novel FOXC1-interacting protein that regulates FOXC1 transcriptional activity in ocular cells.
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|
pubmed:affiliation |
Department of Medical Genetics, University of Alberta, Edmonton, Alberta, Canada.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
