|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0026029,
umls-concept:C0042036,
umls-concept:C0086418,
umls-concept:C0205054,
umls-concept:C0229671,
umls-concept:C0311400,
umls-concept:C0771182,
umls-concept:C0870883,
umls-concept:C1514468,
umls-concept:C1521970,
umls-concept:C1533691,
umls-concept:C1707455
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
1991-9-9
|
|
pubmed:abstractText |
There may be as many as five metabolites of THA in man, four corresponding to products in the rat. The study provides some evidence that one of major metabolites is 1-hydroxy-THA but lends no support to the putative oxidative deamination pathway.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0006-2952
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
25
|
|
pubmed:volume |
42
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
956-9
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:1867652-Animals,
pubmed-meshheading:1867652-Cholinesterase Inhibitors,
pubmed-meshheading:1867652-Chromatography, High Pressure Liquid,
pubmed-meshheading:1867652-Humans,
pubmed-meshheading:1867652-Male,
pubmed-meshheading:1867652-Microsomes, Liver,
pubmed-meshheading:1867652-Rats,
pubmed-meshheading:1867652-Rats, Inbred Strains,
pubmed-meshheading:1867652-Tacrine
|
|
pubmed:year |
1991
|
|
pubmed:articleTitle |
Comparison of the chromatographic characteristics of metabolites of tacrine hydrochloride in human serum and urine with those of in vitro metabolic products from hepatic microsomes.
|
|
pubmed:affiliation |
Department of Medicine, Bristol Royal Infirmary, U.K.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
