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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2008-8-4
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pubmed:abstractText |
C-terminal KCNH2 mutations are commonly associated with a more benign clinical presentation, but mutations localized in close proximity may exhibit different clinical and biophysical phenotypes. The value of detailed cellular characterization of such mutant channels in vitro has not been studied with respect to clinical risk stratification of affected patients.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1556-3871
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pubmed:author |
pubmed-author:AnnekenLarsL,
pubmed-author:BiliczkiPeterP,
pubmed-author:BrandesRalf PRP,
pubmed-author:EhrlichJoachim RJR,
pubmed-author:GirmatsionZenawitZ,
pubmed-author:HarenkampSabineS,
pubmed-author:HerreraDanielD,
pubmed-author:HohnloserStefan HSH,
pubmed-author:MarschallChristophC,
pubmed-author:NattelStanleyS,
pubmed-author:VarroAndrasA
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pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1159-67
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pubmed:dateRevised |
2009-10-27
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pubmed:meshHeading |
pubmed-meshheading:18675227-Adult,
pubmed-meshheading:18675227-Cardiac Electrophysiology,
pubmed-meshheading:18675227-Child, Preschool,
pubmed-meshheading:18675227-Death, Sudden, Cardiac,
pubmed-meshheading:18675227-Ether-A-Go-Go Potassium Channels,
pubmed-meshheading:18675227-Female,
pubmed-meshheading:18675227-Humans,
pubmed-meshheading:18675227-Long QT Syndrome,
pubmed-meshheading:18675227-Middle Aged,
pubmed-meshheading:18675227-Mutation, Missense,
pubmed-meshheading:18675227-Pedigree,
pubmed-meshheading:18675227-Phenotype,
pubmed-meshheading:18675227-Pilot Projects,
pubmed-meshheading:18675227-Risk Assessment,
pubmed-meshheading:18675227-Risk Factors,
pubmed-meshheading:18675227-Torsades de Pointes
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pubmed:year |
2008
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pubmed:articleTitle |
Cellular properties of C-terminal KCNH2 long QT syndrome mutations: description and divergence from clinical phenotypes.
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pubmed:affiliation |
Division of Cardiology, Section of Electrophysiology, JW Goethe-Universität, Frankfurt, Germany.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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