Source:http://linkedlifedata.com/resource/pubmed/id/18675170
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2008-8-4
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pubmed:abstractText |
Neoplasms with perivascular épithelioid-cell differentiation (PEComas) are rare tumors with a distinctive immunoreactivity for melanocytic markers. They have been described in various organs. We report an intrapancreatic PEComa discovered in a 46-year-old woman during a workup for diarrhea. CT scan showed a 1.7cm nodule in the body of the pancreas with slight-contrast enhancement at arterial time and isodense at portal time. The aspect was suggestive of an endocrine tumor despite negative somatostatin-receptor scintigraphy. Enucleation was performed. Pathologic evaluation showed a well-circumscribed intrapancreatic tumor consisting of a population of clear to eosinophilic spindle cells and a less abundant population of epithelioid cells arranged around blood vessels. Tumor cells expressed vimentin, HMB45 and actin and only focally S-100 protein, KL1, CD117 and CD34. These features were consistent with a PEComa. Pancreatic PEComas are rare, but should be included in the differential diagnostic of pancreatic clear cells tumors or pancreatic spindle- and epithelioid-cells tumors.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0242-6498
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pubmed:author |
pubmed-author:BedossaPierreP,
pubmed-author:BelghitiJacquesJ,
pubmed-author:CouvelardAnneA,
pubmed-author:DokmakSafiS,
pubmed-author:HammelPascalP,
pubmed-author:LarochelleOlivierO,
pubmed-author:PérignyMartineM,
pubmed-author:RuszniewskiPhilippeP,
pubmed-author:SauvanetAlainA,
pubmed-author:VilgrainValérieV
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
138-42
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pubmed:meshHeading | |
pubmed:year |
2008
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pubmed:articleTitle |
[Pancreatic perivascular epithelioid cell tumor (PEComa)].
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pubmed:affiliation |
Service d'anatomie pathologique, hôpital Beaujon, AP-HP, université Paris-7 Denis-Diderot, 100, boulevard du Général-Leclerc, 92110 Clichy, France.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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