|
rdf:type |
|
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lifeskim:mentions |
umls-concept:C0021745,
umls-concept:C0080103,
umls-concept:C0266929,
umls-concept:C0450254,
umls-concept:C0580822,
umls-concept:C0678951,
umls-concept:C0879338,
umls-concept:C1518987,
umls-concept:C1547300,
umls-concept:C1548760,
umls-concept:C1550594,
umls-concept:C1554080,
umls-concept:C1706198
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|
pubmed:issue |
8
|
|
pubmed:dateCreated |
2008-8-4
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|
pubmed:abstractText |
The gene polymorphisms interferon-gamma (IFN-gamma) 874 T/A and interleukin (IL)-12 1188 A/C have been associated with the altered production of cytokines. Therefore, they might be indicative of the occurrence of chronic periodontitis (CP) or aggressive periodontitis (AgP) and the prevalence of key periodontal pathogens. For this purpose, we analyzed these polymorphisms in subjects with generalized AgP or generalized CP. Moreover, we assessed the relationship between these polymorphisms and five periodontopathic bacteria.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
D
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0022-3492
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
79
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1434-43
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:18672993-Actinobacillus actinomycetemcomitans,
pubmed-meshheading:18672993-Adenine,
pubmed-meshheading:18672993-Adult,
pubmed-meshheading:18672993-Age Factors,
pubmed-meshheading:18672993-Alleles,
pubmed-meshheading:18672993-Bacteria,
pubmed-meshheading:18672993-Cytosine,
pubmed-meshheading:18672993-Female,
pubmed-meshheading:18672993-Gene Frequency,
pubmed-meshheading:18672993-Genetic Predisposition to Disease,
pubmed-meshheading:18672993-Genotype,
pubmed-meshheading:18672993-Gingival Hemorrhage,
pubmed-meshheading:18672993-Humans,
pubmed-meshheading:18672993-Interferon-gamma,
pubmed-meshheading:18672993-Interleukin-12,
pubmed-meshheading:18672993-Male,
pubmed-meshheading:18672993-Middle Aged,
pubmed-meshheading:18672993-Periodontal Pocket,
pubmed-meshheading:18672993-Periodontitis,
pubmed-meshheading:18672993-Polymerase Chain Reaction,
pubmed-meshheading:18672993-Polymorphism, Genetic,
pubmed-meshheading:18672993-Prevotella intermedia,
pubmed-meshheading:18672993-Sex Factors,
pubmed-meshheading:18672993-Smoking,
pubmed-meshheading:18672993-Thymine
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pubmed:year |
2008
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|
pubmed:articleTitle |
Interferon-gamma and interleukin-12 gene polymorphisms and their relation to aggressive and chronic periodontitis and key periodontal pathogens.
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|
pubmed:affiliation |
Department of Operative Dentistry and Periodontology, University School of Dental Medicine, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany. stefan.reichert@medizin.uni-halle.de
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pubmed:publicationType |
Journal Article,
Comparative Study
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