Linked Life Data

18670613

Source:http://linkedlifedata.com/resource/pubmed/id/18670613

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2008-8-1
pubmed:abstractText
New bidentate or tridentate Schiff bases and their VO(II) and Co(II) complexes formed by the condensation of methyl isobutyl ketone with nicotinamide (mna)/2-amino-4-chlorophenol (map) and 2-hydroxy acetophenone with nicotinamide (han)/isoniazide (hai). Physicochemical characterization has been carried out to determine the structure of the complexes. The FAB mass and thermal data show degradation pattern of the complexes. XRD analysis reveals that all the studied complexes crystallize as tetragonal crystal system. Some of the complexes have been screened for their antimicrobial activity by the well diffusion technique using DMSO as solvent on different species of pathogenic bacteria/fungi, that is, E. coli, S. aureus, S. fecalis, A. niger, T. polysporum, and their antimicrobial potency have been discussed. It has been found that all the complexes are antimicrobially active and show higher activity than the free ligand. Metal chelation affects significantly the antimicrobial/bioactive behavior of the organic ligands.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:issn
0793-0291
pubmed:author
pubmed:issnType
Print
pubmed:volume
2008
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
875410
pubmed:year
2008
pubmed:articleTitle
Synthesis, structural, and biological studies of some schiff bases and their metal complexes.
pubmed:affiliation
Department of Chemistry, Dr. Harisingh Gour University, Sagar (M.P.) 470003, India.
pubmed:publicationType
Journal Article