18668243

Source:http://linkedlifedata.com/resource/pubmed/id/18668243

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0035820, umls-concept:C0140694, umls-concept:C0162638, umls-concept:C0205263, umls-concept:C0533112
pubmed:issue	5
pubmed:dateCreated	2009-2-26
pubmed:abstractText	1-(3-C-Ethynyl-beta-D: -ribo-pentofuranosyl)cytosine (ECyd), a ribonucleoside analog, has a potent cytotoxic activity against cancer cells. The present studies have been performed to elucidate the overall mechanisms of ECyd-induced apoptotic cell death.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7806519
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/1-(3-C-ethynylribopentofuranosyl)cyt..., http://linkedlifedata.com/resource/pubmed/chemical/2-5A-dependent ribonuclease, http://linkedlifedata.com/resource/pubmed/chemical/Cytidine, http://linkedlifedata.com/resource/pubmed/chemical/Endoribonucleases, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Ribosomal, 28S
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	1432-0843
pubmed:author	pubmed-author:FukushimaMasakazuM, pubmed-author:GodaKazatoK, pubmed-author:HiramotoAkikoA, pubmed-author:KimHye-SookHS, pubmed-author:KitadeYukioY, pubmed-author:MatsudaAkiraA, pubmed-author:NaitoTomoharuT, pubmed-author:SasakiTakumaT, pubmed-author:SatoAkiraA, pubmed-author:TakatoriSatoshiS, pubmed-author:WatayaYusukeY, pubmed-author:YokogawaTatsushiT
pubmed:issnType	Electronic
pubmed:volume	63
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	837-50
pubmed:dateRevised	2011-6-17
pubmed:meshHeading	pubmed-meshheading:18668243-Animals, pubmed-meshheading:18668243-Apoptosis, pubmed-meshheading:18668243-Binding, Competitive, pubmed-meshheading:18668243-Blotting, Northern, pubmed-meshheading:18668243-Blotting, Western, pubmed-meshheading:18668243-Cell Proliferation, pubmed-meshheading:18668243-Cytidine, pubmed-meshheading:18668243-Endoribonucleases, pubmed-meshheading:18668243-Enzyme Inhibitors, pubmed-meshheading:18668243-Fibrosarcoma, pubmed-meshheading:18668243-Humans, pubmed-meshheading:18668243-Immunoenzyme Techniques, pubmed-meshheading:18668243-In Situ Nick-End Labeling, pubmed-meshheading:18668243-Mammary Neoplasms, Experimental, pubmed-meshheading:18668243-Membrane Potential, Mitochondrial, pubmed-meshheading:18668243-Mice, pubmed-meshheading:18668243-Mitochondria, pubmed-meshheading:18668243-RNA, Ribosomal, 28S, pubmed-meshheading:18668243-Transfection
pubmed:year	2009
pubmed:articleTitle	Role of RNase L in apoptosis induced by 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine.
pubmed:affiliation	Faculty of Pharmaceutical Sciences, Okayama University, 1-1-1 Tsushimanaka, Okayama, 700-8530, Japan.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't