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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2008-10-10
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pubmed:abstractText |
Growth of alkaliphilic Bacillus halodurans C-125 both on agar plates and in liquid culture was inhibited by methyl-beta-cyclodextrin (CD). Furthermore, resting cells of the strain were lysed by contact with methyl-beta-CD higher than 10 mM. alpha-CD also showed lysis activity against Bacillus and related strains. The activity was not observed with Gram-negative and Gram-positive bacteria except for Bacillus strains. Fluorescence staining and scanning electron microscopy of cells revealed that methyl-beta-CD disrupted cell membranes, and consequently, the cells were lysed. This is a novel physiological property of CDs.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1432-072X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
190
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
605-9
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pubmed:meshHeading |
pubmed-meshheading:18665349-Anti-Bacterial Agents,
pubmed-meshheading:18665349-Bacillus,
pubmed-meshheading:18665349-Cell Membrane,
pubmed-meshheading:18665349-Fluorescent Dyes,
pubmed-meshheading:18665349-Microbial Viability,
pubmed-meshheading:18665349-Microscopy, Electron, Transmission,
pubmed-meshheading:18665349-Staining and Labeling,
pubmed-meshheading:18665349-alpha-Cyclodextrins,
pubmed-meshheading:18665349-beta-Cyclodextrins
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pubmed:year |
2008
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pubmed:articleTitle |
Antibacterial activity of cyclodextrins against Bacillus strains.
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pubmed:affiliation |
Extremobiosphere Research Center of Japan Agency for Marine-Earth Science and Technology (JAMSTEC) 2-15, Natsushima, Yokosuka 237-0061, Japan.
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pubmed:publicationType |
Journal Article
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