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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
14
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pubmed:dateCreated |
2008-8-28
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pubmed:abstractText |
Arginase II (AII) is involved in the polyamine synthetic pathway, and elevated levels of expression have been found in a high proportion of prostate cancer samples and patients. However, the biological function of arginase II in prostate cancer still remains to be elucidated. In this study, we utilized the TRAMP mouse prostate cancer model to better understand the contribution of AII on tumor development.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1097-0045
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1561-9
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:18663728-Adenocarcinoma,
pubmed-meshheading:18663728-Animals,
pubmed-meshheading:18663728-Arginase,
pubmed-meshheading:18663728-Blotting, Western,
pubmed-meshheading:18663728-Cell Line, Tumor,
pubmed-meshheading:18663728-Hyperargininemia,
pubmed-meshheading:18663728-Male,
pubmed-meshheading:18663728-Mice,
pubmed-meshheading:18663728-Mice, Inbred C57BL,
pubmed-meshheading:18663728-Mice, Knockout,
pubmed-meshheading:18663728-Mice, Transgenic,
pubmed-meshheading:18663728-Neoplasms, Hormone-Dependent,
pubmed-meshheading:18663728-Prostatic Neoplasms,
pubmed-meshheading:18663728-RNA, Neoplasm,
pubmed-meshheading:18663728-Receptors, Tumor Necrosis Factor, Member 25,
pubmed-meshheading:18663728-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2008
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pubmed:articleTitle |
Disruption of arginase II alters prostate tumor formation in TRAMP mice.
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pubmed:affiliation |
Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California 90095-1732, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
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