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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2008-7-29
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pubmed:abstractText |
The prevalence of hazardous incidents induced by attentional impairment during night work and ensuing commute times is attributable to circadian misalignment and increased sleep pressure. In a 10-day shift work simulation protocol (4 day shifts and 3 night shifts), the efficacies of 2 countermeasures against nighttime (2300 to 0700 h) attentional impairment were compared: (1) Morning Sleep (0800 to 1600 h; n = 18) in conjunction with a phase-delaying light exposure (2300 to 0300 h), and (2) Evening Sleep (1400 to 2200 h; n = 17) in conjunction with a phase-advancing light exposure (0300 to 0700 h). Analysis of the dim light salivary melatonin onset indicated a modest but significant circadian realignment in both sleep groups (evening sleep: 2.27 +/- 0.6 h phase advance, p < 0.01; morning sleep: 4.98 +/- 0.43 h phase delay, p < 0.01). Daytime sleep efficiency and total sleep time did not differ between them or from their respective baseline sleep (2200 to 0600 h; p > 0.05). However, on the final night shift, the evening sleep subjects had 37% fewer episodes of attentional impairment (long response times: 22 +/- 4 vs. 35 +/- 4; p = 0.02) and quicker responses (p < 0.01) on the Psychomotor Vigilance Task than their morning sleep counterparts. Their response speed recovered to near daytime levels (p = 0.47), whereas those of the morning sleep subjects continued to be slower than their daytime levels (p = 0.008). It is concluded that partial circadian realignment to night work in combination with reduced homeostatic pressure contributed to the greater efficacy of a schedule of Evening Sleep with a phase-advancing light exposure as a countermeasure against attentional impairment, over a schedule of Morning Sleep with a phase-delaying light exposure. These results have important implications for managing patients with shift work disorder.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18663241-10201061,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18663241-10607036,
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0748-7304
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
341-52
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pubmed:dateRevised |
2011-4-26
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pubmed:meshHeading |
pubmed-meshheading:18663241-Adult,
pubmed-meshheading:18663241-Biological Clocks,
pubmed-meshheading:18663241-Circadian Rhythm,
pubmed-meshheading:18663241-Female,
pubmed-meshheading:18663241-Humans,
pubmed-meshheading:18663241-Light,
pubmed-meshheading:18663241-Male,
pubmed-meshheading:18663241-Melatonin,
pubmed-meshheading:18663241-Sleep,
pubmed-meshheading:18663241-Sleep Disorders, Circadian Rhythm,
pubmed-meshheading:18663241-Time Factors,
pubmed-meshheading:18663241-Work Schedule Tolerance
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pubmed:year |
2008
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pubmed:articleTitle |
The impact of sleep timing and bright light exposure on attentional impairment during night work.
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pubmed:affiliation |
Division of Sleep Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA. nsanthi@rics.bwh.harvard.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
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