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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2008-8-25
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pubmed:abstractText |
PTX is one of the most widely used drug in oncology due to its high efficacy against solid tumors and several hematological cancers. PTX is administered in a formulation containing 1:1 Cremophor EL (polyethoxylated castor oil) and ethanol, often responsible for toxic effects. Its encapsulation in colloidal delivery systems would gain an improved targeting to cancer cells, reducing the dose and frequency of administration.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-10210732,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-10958311,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-11245908,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-12204596,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-12363453,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-12490371,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-15161985,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-15161988,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-15685044,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-16021466,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-16024075,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-16132339,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-16314289,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-16364960,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-16474910,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-16618750,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-16713148,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-16928810,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-17048526,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-17092739,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-17118485,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-17646066,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-17657799,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-17716129,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-8142172,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18657273-8904823
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2407
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
212
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:18657273-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:18657273-Cell Line, Tumor,
pubmed-meshheading:18657273-Cell Proliferation,
pubmed-meshheading:18657273-Cell Survival,
pubmed-meshheading:18657273-Chromatography, High Pressure Liquid,
pubmed-meshheading:18657273-Colloids,
pubmed-meshheading:18657273-Coumarins,
pubmed-meshheading:18657273-Drug Carriers,
pubmed-meshheading:18657273-Hematologic Neoplasms,
pubmed-meshheading:18657273-Humans,
pubmed-meshheading:18657273-Lactic Acid,
pubmed-meshheading:18657273-Microscopy, Electron, Scanning,
pubmed-meshheading:18657273-Microscopy, Fluorescence,
pubmed-meshheading:18657273-Neoplasms,
pubmed-meshheading:18657273-Paclitaxel,
pubmed-meshheading:18657273-Polyglycolic Acid
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pubmed:year |
2008
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pubmed:articleTitle |
Paclitaxel loading in PLGA nanospheres affected the in vitro drug cell accumulation and antiproliferative activity.
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pubmed:affiliation |
Dipartimento di Oncologia Sperimentale, Istituto Oncologico del Mediterraneo, Viagrande (CT), Italy. l.vicari@iomricerca.it
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pubmed:publicationType |
Journal Article
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