Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2008-7-25
pubmed:abstractText
Rheumatoid arthritis (RA) is a chronic inflammatory illness that primarily affects the joints. It is associated with symptoms of fatigue, pain, and sleep disturbances that can overlap with or mimic symptoms of depression. Depressive symptoms are highly comorbid with RA and may occur with at least mild severity in up to 42% of RA patients. RA and depression contribute to mortality, decreased quality of life, increased health care costs, and disability. Inflammatory pathways may hold the key to a link between depression and RA, and cytokines have been a major target of research in this area. This article reviews some of the most recent research and commentary on this complex relationship.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1535-1645
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
258-64
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Comorbid depression in rheumatoid arthritis: pathophysiology and clinical implications.
pubmed:affiliation
Department of Neuropsychiatry and Behavioral Sciences, University of South Carolina School of Medicine, 15 Medical Park, 3555 Harden Street Extension, Columbia, SC 29203, USA. tbruce@gw.mp.sc.edu
pubmed:publicationType
Journal Article, Review