Linked Life Data

18651816

Source:http://linkedlifedata.com/resource/pubmed/id/18651816

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2008-7-24
pubmed:abstractText
Surgical-site infections (SSIs) remain a common complication, affecting some 5% of patients undergoing surgical procedures and can sometimes present a major challenge after surgery with life-threatening septic illness. The appearance of organisms that are often resistant to common antibiotic treatment is of great concern. Staphylococcus aureus is the organism most commonly recovered from infected surgical wounds, and usually contaminates wounds from the patients own skin. SSIs occur despite appropriate skin disinfection, sterilization of instruments, use of gown and gloves, appropriate sterile technique and prophylactic antimicrobials. In fact, it is difficult to maintain a sterile field over time, and most wounds become contaminated throughout the course of surgery. Methicillin-resistant S. aureus (MRSA) first arose in the hospital setting, but have more recently evolved in the community. Such community-acquired MRSA are genetically different and seem to be even more virulent owing to genes that encode virulence factors, such as staphylococcal cassette chromosome mec type IV and Panton-Valentine leukocidin. The purpose of this review is to summarize characteristics of frequently isolated bacterial strains from SSIs. The focus will be on Gram-positive organisms because of their increasing prevalence in SSIs and their high potential to develop resistance against several antibiotic agents, including vancomycin.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1746-0921
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
453-62
pubmed:dateRevised
2010-12-30
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Resistance profiles in surgical-site infection.
pubmed:affiliation
Veterans Affairs Medical Center & Department of Surgery, University of Louisville, Louisville, KY 40292, USA. amlenz01@gwise.louisville.edu
pubmed:publicationType
Journal Article, Review