In children with cancer a well-known risk factor for cardiotoxicity is a high cumulative dose of anthracyclines, but little is known about cardiac function in low-dose anthracycline-treated survivors. Also, it is unclear if a safe anthracycline-dose exists at all.
Subdivision Paediatric Oncology, Department of Paediatrics, University Medical Centre Groningen, University of Groningen, P.O. Box 30 001, 9700 RB, Groningen, The Netherlands. c.a.j.brouwer@bkk.umcg.nl