Linked Life Data

18647954

Source:http://linkedlifedata.com/resource/pubmed/id/18647954

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2008-10-30
pubmed:abstractText
A prior genome-wide association (GWA) study in Pima Indians identified variants within PCLO that were associated with early-onset type 2 diabetes. PCLO encodes a presynaptic cytomatrix protein that functions as a Ca(2+) sensor that may be involved in insulin secretion and/or insulin action. Therefore, PCLO was analyzed as a candidate gene for type 2 diabetes.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-10631157, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-11735114, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-12401793, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-14660679, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-15111484, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-15561922, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-16804078, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-17293876, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-17460697, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-17463246, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-17463248, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-17463249, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-17554300, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-17720895, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-17846125, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-18372903, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-2191919, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-736028, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-8247074, http://linkedlifedata.com/resource/pubmed/commentcorrection/18647954-9042926
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1939-327X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3156-60
pubmed:dateRevised
2010-9-21
pubmed:meshHeading
pubmed-meshheading:18647954-Adult, pubmed-meshheading:18647954-Arizona, pubmed-meshheading:18647954-Cytoskeletal Proteins, pubmed-meshheading:18647954-Diabetes Mellitus, Type 2, pubmed-meshheading:18647954-Female, pubmed-meshheading:18647954-Gene Expression Profiling, pubmed-meshheading:18647954-Gene Frequency, pubmed-meshheading:18647954-Genetic Predisposition to Disease, pubmed-meshheading:18647954-Genotype, pubmed-meshheading:18647954-Humans, pubmed-meshheading:18647954-Indians, North American, pubmed-meshheading:18647954-Insulin Resistance, pubmed-meshheading:18647954-Male, pubmed-meshheading:18647954-Middle Aged, pubmed-meshheading:18647954-Neuropeptides, pubmed-meshheading:18647954-Polymorphism, Single Nucleotide, pubmed-meshheading:18647954-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:18647954-Young Adult
pubmed:year
2008
pubmed:articleTitle
PCLO variants are nominally associated with early-onset type 2 diabetes and insulin resistance in Pima Indians.
pubmed:affiliation
Department of Health and HumanServices, Diabetes Molecular Genetics Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and KidneyDiseases, National Institutes of Health, Phoenix, Arizona, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Intramural