Source:http://linkedlifedata.com/resource/pubmed/id/18647634
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
41
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pubmed:dateCreated |
2008-9-10
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pubmed:abstractText |
There is increasing interest in routine vaccination of children against influenza. We use an age-structured model to demonstrate that the long-term incidence of influenza A could decrease by 11-21% in the overall population by vaccinating individuals aged 6 to <24 months, and by 22-38% and 65-97% through targeting those aged 6 to <60 months and 6 months to 16 years, respectively. The corresponding reductions predicted for influenza B were 25-35%, 44-69% and 85-96%, respectively. These results are sensitive to assumptions about contact patterns and several parameters, including the vaccine efficacy among those aged <24 months, require further study. Consistently high levels of vaccination coverage among pre-school children has the potential to bring benefits to both those vaccinated and the community.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0264-410X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
26
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5321-30
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pubmed:meshHeading |
pubmed-meshheading:18647634-Adolescent,
pubmed-meshheading:18647634-Child,
pubmed-meshheading:18647634-Child, Preschool,
pubmed-meshheading:18647634-England,
pubmed-meshheading:18647634-Humans,
pubmed-meshheading:18647634-Immunization Programs,
pubmed-meshheading:18647634-Infant,
pubmed-meshheading:18647634-Influenza, Human,
pubmed-meshheading:18647634-Influenza Vaccines,
pubmed-meshheading:18647634-Models, Theoretical,
pubmed-meshheading:18647634-Vaccination,
pubmed-meshheading:18647634-Wales
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pubmed:year |
2008
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pubmed:articleTitle |
Estimating the impact of childhood influenza vaccination programmes in England and Wales.
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pubmed:affiliation |
Modelling and Economics Unit, Health Protection Agency Centre for Infections, 61 Colindale Avenue, Colindale, London NW9 5HT, UK. emilia.vynnycky@hpa.org.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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