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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2008-7-23
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pubmed:abstractText |
Cerebral vasospasm has been the dreaded complication of ruptured intracranial aneurysms. Worldwide effort has led to many promising experimental treatments but none was confirmed to be effective in clinical trials. Ecdysterone is an insect steroid hormone. Our previous study showed that ecdysterone might prevent cerebral vasospasm in vitro. Even after all these works, rare attempts have been made to test the effect of ecdysterone on vascular adventitial fibroblast (VAF) proliferation, a process known to play an important role in various pathogenic vascular conditions. Thus, we tested the hypothesis that ecdysterone could affect VAF characteristics and have an effect on SAH induced cerebral vasospasm.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-10362662,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-10517736,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-10615057,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-10662750,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-10720681,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-10736277,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-10763512,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-11450013,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-11739275,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-12610309,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-12823881,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-16282541,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-2274134,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-2891067,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-2983068,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-3188126,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-3808241,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-3883222,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-8925587,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-9488312,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18647496-9668192
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0161-6412
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
571-80
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:18647496-Animals,
pubmed-meshheading:18647496-Aorta,
pubmed-meshheading:18647496-Behavior, Animal,
pubmed-meshheading:18647496-Cell Cycle,
pubmed-meshheading:18647496-Cell Movement,
pubmed-meshheading:18647496-Cells, Cultured,
pubmed-meshheading:18647496-Cerebral Angiography,
pubmed-meshheading:18647496-Disease Models, Animal,
pubmed-meshheading:18647496-Ecdysterone,
pubmed-meshheading:18647496-Female,
pubmed-meshheading:18647496-Fibroblasts,
pubmed-meshheading:18647496-Male,
pubmed-meshheading:18647496-Microscopy, Electron, Transmission,
pubmed-meshheading:18647496-Oxyhemoglobins,
pubmed-meshheading:18647496-Rabbits,
pubmed-meshheading:18647496-Rats,
pubmed-meshheading:18647496-Rats, Sprague-Dawley,
pubmed-meshheading:18647496-Subarachnoid Hemorrhage,
pubmed-meshheading:18647496-Time Factors,
pubmed-meshheading:18647496-Ultrasonography, Doppler, Transcranial,
pubmed-meshheading:18647496-Vasospasm, Intracranial
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pubmed:year |
2008
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pubmed:articleTitle |
The effect of ecdysterone on cerebral vasospasm following experimental subarachnoid hemorrhage in vitro and in vivo.
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pubmed:affiliation |
Department of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing, China.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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