|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2008-9-22
|
|
pubmed:abstractText |
Current approaches to colonic drug delivery exploit one of two main physiological characteristics: the pH change or increase in bacterial numbers along the gastrointestinal tract. Here, we describe a new concept in targeted delivery, which combines these triggers to improve colonic delivery.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
1365-2036
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
1
|
|
pubmed:volume |
28
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
911-6
|
|
pubmed:meshHeading |
pubmed-meshheading:18647282-Adult,
pubmed-meshheading:18647282-Analysis of Variance,
pubmed-meshheading:18647282-Colon, Ascending,
pubmed-meshheading:18647282-Drug Delivery Systems,
pubmed-meshheading:18647282-Enterobacteriaceae,
pubmed-meshheading:18647282-Food,
pubmed-meshheading:18647282-Gastrointestinal Transit,
pubmed-meshheading:18647282-Humans,
pubmed-meshheading:18647282-Hydrogen-Ion Concentration,
pubmed-meshheading:18647282-Isotope Labeling,
pubmed-meshheading:18647282-Male,
pubmed-meshheading:18647282-Tablets, Enteric-Coated
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
A new concept in colonic drug targeting: a combined pH-responsive and bacterially-triggered drug delivery technology.
|
|
pubmed:affiliation |
Department of Pharmaceutics, The School of Pharmacy, University of London, London, UK.
|
|
pubmed:publicationType |
Journal Article,
Controlled Clinical Trial,
Research Support, Non-U.S. Gov't
|
