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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2008-9-8
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pubmed:abstractText |
Coenzyme Q10 (CoQ10) is a naturally occurring compound that plays a fundamental role in cellular bioenergetics and is an effective antioxidant. Numerous health benefits of CoQ10 supplementation have been reported, resulting in growing demands for its use in fortifying food. Due to its insolubility in water, the enrichment of most food products is not easily achievable and its in vivo bioavailability is known to be poor. Water solubility was increased significantly with the use of an inclusion complex with beta-cyclodextrin. This complex is widely used as Q10Vital in the food industry, while its in vivo absorption in humans has not previously been studied.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1421-9697
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pubmed:author |
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pubmed:copyrightInfo |
2008 S. Karger AG, Basel.
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pubmed:issnType |
Electronic
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
281-7
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pubmed:meshHeading |
pubmed-meshheading:18645245-Administration, Oral,
pubmed-meshheading:18645245-Adult,
pubmed-meshheading:18645245-Antioxidants,
pubmed-meshheading:18645245-Area Under Curve,
pubmed-meshheading:18645245-Biological Availability,
pubmed-meshheading:18645245-Capsules,
pubmed-meshheading:18645245-Chromatography, High Pressure Liquid,
pubmed-meshheading:18645245-Cross-Over Studies,
pubmed-meshheading:18645245-Female,
pubmed-meshheading:18645245-Food Additives,
pubmed-meshheading:18645245-Humans,
pubmed-meshheading:18645245-Intestinal Absorption,
pubmed-meshheading:18645245-Male,
pubmed-meshheading:18645245-Middle Aged,
pubmed-meshheading:18645245-Solubility,
pubmed-meshheading:18645245-Ubiquinone,
pubmed-meshheading:18645245-Vitamins,
pubmed-meshheading:18645245-beta-Cyclodextrins
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pubmed:year |
2008
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pubmed:articleTitle |
Relative bioavailability of two forms of a novel water-soluble coenzyme Q10.
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pubmed:affiliation |
National Institute of Chemistry, University of Ljubljana, Ljubljana, Slovenia. janko.zmitek@ki.si
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial
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