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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1991-9-9
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pubmed:databankReference |
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pubmed:abstractText |
The ERG3 gene from Saccharomyces cerevisiae has been cloned by complementation of an erg3-2 mutation. ERG3 is the putative gene encoding the C-5 sterol desaturase required for ergosterol biosynthesis. The functional gene has been localized on a 2.5-kb HindIII-BamHI fragment containing an open reading frame comprising 365 amino acids. Gene disruption resulting from a deletion/substitution demonstrates that ERG3 is not essential for cell viability or the sparking function.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0378-1119
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
102
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pubmed:geneSymbol |
ERG3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
39-44
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1864507-Amino Acid Sequence,
pubmed-meshheading:1864507-Base Sequence,
pubmed-meshheading:1864507-Blotting, Southern,
pubmed-meshheading:1864507-Cloning, Molecular,
pubmed-meshheading:1864507-Ergosterol,
pubmed-meshheading:1864507-Frameshift Mutation,
pubmed-meshheading:1864507-Molecular Sequence Data,
pubmed-meshheading:1864507-Mutagenesis, Insertional,
pubmed-meshheading:1864507-Oxidoreductases,
pubmed-meshheading:1864507-Restriction Mapping,
pubmed-meshheading:1864507-Saccharomyces cerevisiae,
pubmed-meshheading:1864507-Sterols
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pubmed:year |
1991
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pubmed:articleTitle |
Cloning, disruption and sequence of the gene encoding yeast C-5 sterol desaturase.
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pubmed:affiliation |
Department of Biology, Indiana University-Purdue University at Indianapolis 46205.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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