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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2008-8-11
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pubmed:abstractText |
Intercross studies in inbred mice susceptible or resistant to liver fibrosis revealed complement factor 5 as a quantitative trait gene associated with the development of fibrosis. In 277 patients with hepatitis C, two C5 SNPs, rs17611 and rs2300929, have been associated with advanced fibrosis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0168-8278
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pubmed:author |
pubmed-author:BergThomasT,
pubmed-author:BergkAlexandraA,
pubmed-author:BuggischPeterP,
pubmed-author:HalangkJulianeJ,
pubmed-author:HinrichsenHolgerH,
pubmed-author:KlinkerHartwigH,
pubmed-author:LandtOlfertO,
pubmed-author:MuellerTobiasT,
pubmed-author:NeuhausPeterP,
pubmed-author:NeumannKonradK,
pubmed-author:PuhlGeroG,
pubmed-author:SarrazinChristophC,
pubmed-author:TeuberGerlindeG,
pubmed-author:WeichViolaV,
pubmed-author:WiedenmannBertramB,
pubmed-author:WittHeikoH
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pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
339-45
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pubmed:meshHeading |
pubmed-meshheading:18644651-Adolescent,
pubmed-meshheading:18644651-Adult,
pubmed-meshheading:18644651-Aged,
pubmed-meshheading:18644651-Aged, 80 and over,
pubmed-meshheading:18644651-Cohort Studies,
pubmed-meshheading:18644651-Complement C5,
pubmed-meshheading:18644651-Europe,
pubmed-meshheading:18644651-Female,
pubmed-meshheading:18644651-Gene Frequency,
pubmed-meshheading:18644651-Genetic Predisposition to Disease,
pubmed-meshheading:18644651-Genotype,
pubmed-meshheading:18644651-Germany,
pubmed-meshheading:18644651-Haplotypes,
pubmed-meshheading:18644651-Hepatitis C, Chronic,
pubmed-meshheading:18644651-Humans,
pubmed-meshheading:18644651-Liver Cirrhosis,
pubmed-meshheading:18644651-Male,
pubmed-meshheading:18644651-Middle Aged,
pubmed-meshheading:18644651-Polymorphism, Single Nucleotide,
pubmed-meshheading:18644651-Risk Factors
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pubmed:year |
2008
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pubmed:articleTitle |
Evaluation of complement factor 5 variants as genetic risk factors for the development of advanced fibrosis in chronic hepatitis C infection.
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pubmed:affiliation |
Medizinische Klinik mit Schwerpunkt Hepatologie und Gastroenterologie, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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