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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2009-6-29
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pubmed:abstractText |
Colorectal cancers may demonstrate chromosomal instability (CSI) or microsatellite instability (MSI-H). A third group of microsatellite and chromosome stable (MACS) colorectal cancer has been described more recently. Patients with MSI-H colorectal cancers demonstrate improved outcome and a pronounced inflammatory infiltrate. Enhanced host immune response and increased immunogenicity might explain these observations. This study aims to further characterize colorectal cancer immunogenicity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1463-1318
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
601-8
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:18637931-Aged,
pubmed-meshheading:18637931-Aged, 80 and over,
pubmed-meshheading:18637931-Aneuploidy,
pubmed-meshheading:18637931-Cell Proliferation,
pubmed-meshheading:18637931-Chromosomal Instability,
pubmed-meshheading:18637931-Colorectal Neoplasms,
pubmed-meshheading:18637931-Diploidy,
pubmed-meshheading:18637931-Disease-Free Survival,
pubmed-meshheading:18637931-Female,
pubmed-meshheading:18637931-Follow-Up Studies,
pubmed-meshheading:18637931-Humans,
pubmed-meshheading:18637931-Immunogenetic Phenomena,
pubmed-meshheading:18637931-Kaplan-Meier Estimate,
pubmed-meshheading:18637931-Lymphocytes,
pubmed-meshheading:18637931-Male,
pubmed-meshheading:18637931-Microsatellite Instability,
pubmed-meshheading:18637931-Middle Aged,
pubmed-meshheading:18637931-Neoplasm Recurrence, Local,
pubmed-meshheading:18637931-Phenotype
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pubmed:year |
2009
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pubmed:articleTitle |
Microsatellite and chromosomal stable colorectal cancers demonstrate poor immunogenicity and early disease recurrence.
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pubmed:affiliation |
SpR General Surgery, North East Thames Region, UK. ayanbanerjea@hotmail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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