Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-9-12
pubmed:abstractText
Hypomagnesemia is a common disorder in noncardiac surgical patients in the postoperative period, but the effect of cardiac surgery on serum magnesium concentrations remains unclear. The authors hypothesized that cardiac surgery is associated with hypomagnesemia, and prospectively studied 101 subjects (60 +/- 13.1 years of age) undergoing coronary artery revascularization (n = 70), valve replacement (n = 24), or both simultaneously (n = 7). Blood samples and clinical biochemical data were collected before induction of anesthesia, prior to cardiopulmonary bypass (CPB), immediately after CPB, and on postoperative day 1. Blood samples were analyzed for ultrafilterable magnesium, total magnesium, ionized calcium, parathyroid hormone, and free fatty acid concentrations. Outcome variables were also determined. Eighteen of 99 (18.2%) subjects had hypomagnesemia preinduction and this number increased to 71 of 100 (71.0%) following cessation of CPB (P less than 0.05). Patients with postoperative hypomagnesemia had a higher frequency of atrial dysrhythmias (22 of 71 [31.0%] v 3 of 29 [10.3%], P less than 0.05) and required prolonged mechanical ventilatory support (22 of 63 [34.9%] v 4 of 33 [12.1%], P less than 0.05). Hypomagnesemia is common following cardiac surgical procedures with CPB and is associated with clinically important postoperative morbidity.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1053-0770
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
201-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:1863738-Adult, pubmed-meshheading:1863738-Aged, pubmed-meshheading:1863738-Aged, 80 and over, pubmed-meshheading:1863738-Aortic Valve, pubmed-meshheading:1863738-Arrhythmias, Cardiac, pubmed-meshheading:1863738-Cardiac Surgical Procedures, pubmed-meshheading:1863738-Cardiopulmonary Bypass, pubmed-meshheading:1863738-Coronary Artery Bypass, pubmed-meshheading:1863738-Female, pubmed-meshheading:1863738-Heart Failure, pubmed-meshheading:1863738-Heart Valve Prosthesis, pubmed-meshheading:1863738-Homeostasis, pubmed-meshheading:1863738-Humans, pubmed-meshheading:1863738-Hypokalemia, pubmed-meshheading:1863738-Magnesium, pubmed-meshheading:1863738-Male, pubmed-meshheading:1863738-Middle Aged, pubmed-meshheading:1863738-Mitral Valve, pubmed-meshheading:1863738-Postoperative Complications, pubmed-meshheading:1863738-Prospective Studies, pubmed-meshheading:1863738-Respiratory Insufficiency, pubmed-meshheading:1863738-Risk Factors, pubmed-meshheading:1863738-Ultrafiltration
pubmed:year
1991
pubmed:articleTitle
Hypomagnesemia is common following cardiac surgery.
pubmed:affiliation
Department of Anesthesia, Brigham and Women's Hospital/Harvard Medical School, Boston, MA 02114.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't