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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8 Pt 1
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pubmed:dateCreated |
2008-8-13
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pubmed:abstractText |
Proton pump inhibitors (PPI) are mainly metabolized by cytochrome P450 2C19 (CYP2C19) in the liver. We investigated whether the CYP2C19 genotype plays a role in the eradication rate of Helicobacter pylori (H. pylori) infection in patients receiving pantoprazole- or esomeprazole-based triple therapy.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1440-1746
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1287-91
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pubmed:meshHeading |
pubmed-meshheading:18637061-2-Pyridinylmethylsulfinylbenzimidazoles,
pubmed-meshheading:18637061-Adult,
pubmed-meshheading:18637061-Amoxicillin,
pubmed-meshheading:18637061-Anti-Bacterial Agents,
pubmed-meshheading:18637061-Aryl Hydrocarbon Hydroxylases,
pubmed-meshheading:18637061-Clarithromycin,
pubmed-meshheading:18637061-Drug Therapy, Combination,
pubmed-meshheading:18637061-Female,
pubmed-meshheading:18637061-Helicobacter Infections,
pubmed-meshheading:18637061-Helicobacter pylori,
pubmed-meshheading:18637061-Humans,
pubmed-meshheading:18637061-Male,
pubmed-meshheading:18637061-Middle Aged,
pubmed-meshheading:18637061-Omeprazole,
pubmed-meshheading:18637061-Polymorphism, Genetic,
pubmed-meshheading:18637061-Proton Pump Inhibitors,
pubmed-meshheading:18637061-Treatment Outcome
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pubmed:year |
2008
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pubmed:articleTitle |
Effect of the CYP2C19 polymorphism on the eradication rate of Helicobacter pylori infection by 7-day triple therapy with regular proton pump inhibitor dosage.
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pubmed:affiliation |
Department of Internal Medicine and Liver Research Institute, Seoul National University Bundang Hospital, Seongnam, Gyeonggi-do, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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