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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2008-9-18
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pubmed:abstractText |
The purpose of this study was to identify rare APOA5 variants in 130 severe hypertriglyceridemic patients by sequencing, and to test their functionality, since no patient recall was possible.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1524-4636
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pubmed:author |
pubmed-author:CooperJ AJA,
pubmed-author:DelsauxNN,
pubmed-author:DichlbergerAA,
pubmed-author:DorfmeisterBB,
pubmed-author:HeerenJJ,
pubmed-author:HubacekJ AJA,
pubmed-author:HumphriesS ESE,
pubmed-author:KasteleinJ J PJJ,
pubmed-author:KuivenhovenJ AJA,
pubmed-author:LeeP JPJ,
pubmed-author:LinzGG,
pubmed-author:LookeneAA,
pubmed-author:MerkelMM,
pubmed-author:NiermanMM,
pubmed-author:NilssonS KSK,
pubmed-author:OlivecronaGG,
pubmed-author:PuttWW,
pubmed-author:SchaapF GFG,
pubmed-author:SchneiderW JWJ,
pubmed-author:TalmudP JPJ,
pubmed-author:VrablikMM,
pubmed-author:WhittallRR,
pubmed-author:ZengW WWW
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pubmed:issnType |
Electronic
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1866-71
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pubmed:meshHeading |
pubmed-meshheading:18635818-Adult,
pubmed-meshheading:18635818-Apolipoproteins A,
pubmed-meshheading:18635818-DNA Mutational Analysis,
pubmed-meshheading:18635818-Europe,
pubmed-meshheading:18635818-Female,
pubmed-meshheading:18635818-Heterozygote,
pubmed-meshheading:18635818-Homozygote,
pubmed-meshheading:18635818-Humans,
pubmed-meshheading:18635818-Hydrolysis,
pubmed-meshheading:18635818-Hypertriglyceridemia,
pubmed-meshheading:18635818-Lipoprotein Lipase,
pubmed-meshheading:18635818-Lipoproteins, VLDL,
pubmed-meshheading:18635818-Male,
pubmed-meshheading:18635818-Models, Molecular,
pubmed-meshheading:18635818-Mutation, Missense,
pubmed-meshheading:18635818-Phenotype,
pubmed-meshheading:18635818-Pregnancy,
pubmed-meshheading:18635818-Pregnancy Complications,
pubmed-meshheading:18635818-Protein Binding,
pubmed-meshheading:18635818-Protein Conformation,
pubmed-meshheading:18635818-Receptors, LDL,
pubmed-meshheading:18635818-Recombinant Proteins,
pubmed-meshheading:18635818-Severity of Illness Index,
pubmed-meshheading:18635818-Structure-Activity Relationship,
pubmed-meshheading:18635818-Surface Plasmon Resonance,
pubmed-meshheading:18635818-Triglycerides
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pubmed:year |
2008
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pubmed:articleTitle |
Effects of six APOA5 variants, identified in patients with severe hypertriglyceridemia, on in vitro lipoprotein lipase activity and receptor binding.
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pubmed:affiliation |
Department of Medicine, Division of Cardiovascular Genetics, UCL, London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
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